… derivative of the Lewis blood group antigen structure, also is a … link between ligand binding
and E-selectin conformational … sLe x presenting on the mucin protein) for detecting breast …

… rise to the core 1 to 4 of mucin type O-glycan or to the Tn antigen which can be sialylated.
The core 1 disaccharide structure is called T antigen and, as Tn antigen, can be sialylated. …

… by addition of SLe x and sialyl-Lewis a (SLe a ) structures on either … cells, and mucin-like
tumor antigens carrying SLe x and SLe … of E-selectin in mouse liver causes carcinoma cells that …

… their prototypical binding determinant, sialyl Lewis X (sLeX; … The PSGL-1 molecule (CD162)
is a homodimeric, mucin-like … as “anti-cutaneous lymphocyte antigen”). This is tautological …

… to be processed through both the mucin-type O-glycosylation (… the binding of sLeX to its
endogenous receptor E-selectin (… Cutaneous lymphocyte antigens (CLA) carry sLeX glycans, …

… of sialyl Lewis X (SLeX) levels [16]. It is also well documented that these sialylated Lewis
antigens mediate binding to E-selectin, … support that NCL carrying sialylated antigens may help …

… occurring due to cellular and metabolic changes, exists in almost all … are carbohydrate antigens
derived from mucins, glycoproteins … Since sialyl Lewis X antigens are present in > 90% of …

… Interactions of E-selectin with its ligand sialyl-Lewis X have … responsible for the initial step
in mucin O-glycan synthesis [… high levels of E-selectin ligands such as sLe X antigens, can …

… to be processed through both the mucin-type Oglycosylation (… binding studies have
established that E-selectin binding to … Cutaneous lymphocyte antigens (CLA) carry sLeX glycans …

… Sialyl Lewis antigens biosynthesis is a complex process … cells and gain of E-selectin
binding capacity of cancer cells, … (TAG-72) mucin carrying the STn antigen 75 , whereas CA19-…